Entity Details

Primary name BBC3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BXH1
EntryNameBBC3_HUMAN
FullNameBcl-2-binding component 3, isoforms 1/2
TaxID9606
Evidenceevidence at protein level
Length193
SequenceStatuscomplete
DateCreated2004-12-21
DateModified2021-06-02

Ontological Relatives

GenesBBC3

GO terms

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GOName
GO:0001836 release of cytochrome c from mitochondria
GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0008340 determination of adult lifespan
GO:0031334 positive regulation of protein-containing complex assembly
GO:0032464 positive regulation of protein homooligomerization
GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration
GO:0034976 response to endoplasmic reticulum stress
GO:0042981 regulation of apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0045926 negative regulation of growth
GO:0051209 release of sequestered calcium ion into cytosol
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070245 positive regulation of thymocyte apoptotic process
GO:0071456 cellular response to hypoxia
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0097190 apoptotic signaling pathway
GO:0097194 execution phase of apoptosis
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1903896 positive regulation of IRE1-mediated unfolded protein response
GO:2001056 positive regulation of cysteine-type endopeptidase activity
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR031661 Bcl-2-binding component 3FamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
BBC3_HUMANMCL1_MOUSEIntAct, MINT15694340 20627101 details
BBC3_HUMANB2LA1_MOUSEIntAct15694340 details