Entity Details

Primary name CAR11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BXL7
EntryNameCAR11_HUMAN
FullNameCaspase recruitment domain-containing protein 11
TaxID9606
Evidenceevidence at protein level
Length1154
SequenceStatuscomplete
DateCreated2002-01-31
DateModified2021-06-02

Ontological Relatives

GenesCARD11

GO terms

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GOName
GO:0001772 immunological synapse
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0004385 guanylate kinase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0030183 B cell differentiation
GO:0030890 positive regulation of B cell proliferation
GO:0031295 T cell costimulation
GO:0032449 CBM complex
GO:0032743 positive regulation of interleukin-2 production
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0038202 TORC1 signaling
GO:0042100 B cell proliferation
GO:0042102 positive regulation of T cell proliferation
GO:0042981 regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045061 thymic T cell selection
GO:0045121 membrane raft
GO:0045577 regulation of B cell differentiation
GO:0045580 regulation of T cell differentiation
GO:0048872 homeostasis of number of cells
GO:0050700 CARD domain binding
GO:0050852 T cell receptor signaling pathway
GO:0050862 positive regulation of T cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane raft

Domains

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DomainNameCategoryType
IPR001315 CARD domainDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR033538 Caspase recruitment domain-containing protein 11FamilyFamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR042141 CARD11, CARD domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CAR11_HUMANKC1A_MOUSEDIP19118383 details
CAR11_HUMANM4K1_MOUSEDIP19706536 details