Entity Details

Primary name CBP_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP45481
EntryNameCBP_MOUSE
FullNameHistone lysine acetyltransferase CREBBP
TaxID10090
Evidenceevidence at protein level
Length2441
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000123 histone acetyltransferase complex
GO:0000785 chromatin
GO:0000940 outer kinetochore
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0001093 TFIIB-class transcription factor binding
GO:0002039 p53 binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003684 damaged DNA binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0004402 histone acetyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006473 protein acetylation
GO:0008134 transcription factor binding
GO:0008140 cAMP response element binding protein binding
GO:0008270 zinc ion binding
GO:0008283 cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0016407 acetyltransferase activity
GO:0016573 histone acetylation
GO:0016604 nuclear body
GO:0016605 PML body
GO:0018076 N-terminal peptidyl-lysine acetylation
GO:0019904 protein domain specific binding
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030718 germ-line stem cell population maintenance
GO:0031490 chromatin DNA binding
GO:0031648 protein destabilization
GO:0032688 negative regulation of interferon-beta production
GO:0032793 positive regulation of CREB transcription factor activity
GO:0032991 protein-containing complex
GO:0034644 cellular response to UV
GO:0035729 cellular response to hepatocyte growth factor stimulus
GO:0042975 peroxisome proliferator activated receptor binding
GO:0043426 MRF binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046332 SMAD binding
GO:0048511 rhythmic process
GO:0048525 negative regulation of viral process
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0060325 face morphogenesis
GO:0060355 positive regulation of cell adhesion molecule production
GO:0061733 peptide-lysine-N-acetyltransferase activity
GO:0090575 RNA polymerase II transcription regulator complex
GO:0097718 disordered domain specific binding
GO:0098586 cellular response to virus
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1990258 histone glutamine methylation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000197 Zinc finger, TAZ-typeDomainDomain
IPR000433 Zinc finger, ZZ-typeDomainDomain
IPR001487 BromodomainDomainDomain
IPR003101 Coactivator CBP, KIX domainDomainDomain
IPR009110 Nuclear receptor coactivator, interlockingFamilyHomologous superfamily
IPR010303 CREB-binding protein/p300, atypical RING domainDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR013178 Histone acetyltransferase Rtt109/CBPFamilyFamily
IPR014744 Nuclear receptor coactivator, CREB-bp-like, interlockingDomainDomain
IPR018359 Bromodomain, conserved siteSiteConserved site
IPR031162 CBP/p300-type histone acetyltransferase domainDomainDomain
IPR035898 TAZ domain superfamilyFamilyHomologous superfamily
IPR036427 Bromodomain-like superfamilyFamilyHomologous superfamily
IPR036529 Coactivator CBP, KIX domain superfamilyFamilyHomologous superfamily
IPR037073 Nuclear receptor coactivator, CREB-bp-like, interlocking domain superfamilyFamilyHomologous superfamily
IPR038547 CBP/p300, atypical RING domain superfamilyFamilyHomologous superfamily
IPR043145 Zinc finger, ZZ-type superfamilyFamilyHomologous superfamily

Diseases

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