Entity Details

Primary name SYT1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP46096
EntryNameSYT1_MOUSE
FullNameSynaptotagmin-1
TaxID10090
Evidenceevidence at protein level
Length421
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesSyt1

GO terms

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GOName
GO:0000149 SNARE binding
GO:0001786 phosphatidylserine binding
GO:0005509 calcium ion binding
GO:0005513 detection of calcium ion
GO:0005516 calmodulin binding
GO:0005543 phospholipid binding
GO:0005544 calcium-dependent phospholipid binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0007269 neurotransmitter secretion
GO:0007420 brain development
GO:0008021 synaptic vesicle
GO:0008022 protein C-terminus binding
GO:0014059 regulation of dopamine secretion
GO:0016079 synaptic vesicle exocytosis
GO:0016192 vesicle-mediated transport
GO:0017075 syntaxin-1 binding
GO:0017156 calcium-ion regulated exocytosis
GO:0017158 regulation of calcium ion-dependent exocytosis
GO:0019905 syntaxin binding
GO:0030141 secretory granule
GO:0030154 cell differentiation
GO:0030276 clathrin binding
GO:0030285 integral component of synaptic vesicle membrane
GO:0030348 syntaxin-3 binding
GO:0030424 axon
GO:0030672 synaptic vesicle membrane
GO:0031045 dense core granule
GO:0031340 positive regulation of vesicle fusion
GO:0033603 positive regulation of dopamine secretion
GO:0042584 chromaffin granule membrane
GO:0042734 presynaptic membrane
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043229 intracellular organelle
GO:0044306 neuron projection terminus
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0046982 protein heterodimerization activity
GO:0048278 vesicle docking
GO:0048306 calcium-dependent protein binding
GO:0048488 synaptic vesicle endocytosis
GO:0048791 calcium ion-regulated exocytosis of neurotransmitter
GO:0050750 low-density lipoprotein particle receptor binding
GO:0050806 positive regulation of synaptic transmission
GO:0051291 protein heterooligomerization
GO:0051592 response to calcium ion
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0060076 excitatory synapse
GO:0061669 spontaneous neurotransmitter secretion
GO:0061891 calcium ion sensor activity
GO:0070382 exocytic vesicle
GO:0071277 cellular response to calcium ion
GO:0071911 synchronous neurotransmitter secretion
GO:0098686 hippocampal mossy fiber to CA3 synapse
GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter
GO:0098978 glutamatergic synapse
GO:0099502 calcium-dependent activation of synaptic vesicle fusion
GO:1903235 positive regulation of calcium ion-dependent exocytosis of neurotransmitter
GO:1903305 regulation of regulated secretory pathway
GO:1903861 positive regulation of dendrite extension
GO:2000300 regulation of synaptic vesicle exocytosis

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR001565 SynaptotagminDomainDomain
IPR015428 Synaptotagmin 1FamilyFamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily

Diseases

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