Entity Details

Primary name TOLIP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H0E2
EntryNameTOLIP_HUMAN
FullNameToll-interacting protein
TaxID9606
Evidenceevidence at protein level
Length274
SequenceStatuscomplete
DateCreated2002-03-27
DateModified2021-06-02

Ontological Relatives

GenesTOLLIP

GO terms

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GOName
GO:0005150 interleukin-1, type I receptor binding
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006914 autophagy
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0016310 phosphorylation
GO:0016604 nuclear body
GO:0019900 kinase binding
GO:0030855 epithelial cell differentiation
GO:0031624 ubiquitin conjugating enzyme binding
GO:0031625 ubiquitin protein ligase binding
GO:0032183 SUMO binding
GO:0032991 protein-containing complex
GO:0033235 positive regulation of protein sumoylation
GO:0035325 Toll-like receptor binding
GO:0035578 azurophil granule lumen
GO:0035580 specific granule lumen
GO:0036010 protein localization to endosome
GO:0043130 ubiquitin binding
GO:0043312 neutrophil degranulation
GO:0045087 innate immune response
GO:0045321 leukocyte activation
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular exosome
GO:0070498 interleukin-1-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR003892 Ubiquitin system component CUEDomainDomain
IPR009060 UBA-like superfamilyFamilyHomologous superfamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR037301 Toll-interacting protein, C2 domainDomainDomain
IPR041799 Toll-interacting protein, CUE domainDomainDomain

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink