Entity Details

Primary name ALDH2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP47738
EntryNameALDH2_MOUSE
FullNameAldehyde dehydrogenase, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length519
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesAldh2

GO terms

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GOName
GO:0004029 aldehyde dehydrogenase (NAD+) activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006068 ethanol catabolic process
GO:0006117 acetaldehyde metabolic process
GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0014070 response to organic cyclic compound
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity
GO:0048149 behavioral response to ethanol
GO:0050727 regulation of inflammatory response
GO:0051287 NAD binding
GO:0070404 NADH binding
GO:0110095 cellular detoxification of aldehyde
GO:2000377 regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR015590 Aldehyde dehydrogenase domainDomainDomain
IPR016160 Aldehyde dehydrogenase, cysteine active siteSiteConserved site
IPR016161 Aldehyde/histidinol dehydrogenaseFamilyHomologous superfamily
IPR016162 Aldehyde dehydrogenase, N-terminalFamilyHomologous superfamily
IPR016163 Aldehyde dehydrogenase, C-terminalFamilyHomologous superfamily
IPR029510 Aldehyde dehydrogenase, glutamic acid active siteSiteConserved site

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ALDH2_MOUSESIR3_MOUSEMINT21720390 details