Entity Details

Primary name CCR7_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP47774
EntryNameCCR7_MOUSE
FullNameC-C chemokine receptor type 7
TaxID10090
Evidenceevidence at protein level
Length378
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesCcr7

GO terms

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GOName
GO:0001768 establishment of T cell polarity
GO:0002408 myeloid dendritic cell chemotaxis
GO:0002518 lymphocyte chemotaxis across high endothelial venule
GO:0002606 positive regulation of dendritic cell antigen processing and presentation
GO:0002649 regulation of tolerance induction to self antigen
GO:0002885 positive regulation of hypersensitivity
GO:0002922 positive regulation of humoral immune response
GO:0004930 G protein-coupled receptor activity
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007257 obsolete activation of JUN kinase activity
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010759 positive regulation of macrophage chemotaxis
GO:0010820 positive regulation of T cell chemotaxis
GO:0016021 integral component of membrane
GO:0016493 C-C chemokine receptor activity
GO:0019722 calcium-mediated signaling
GO:0019957 C-C chemokine binding
GO:0030036 actin cytoskeleton organization
GO:0032496 response to lipopolysaccharide
GO:0032649 regulation of interferon-gamma production
GO:0032651 regulation of interleukin-1 beta production
GO:0032695 negative regulation of interleukin-12 production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032735 positive regulation of interleukin-12 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0034695 response to prostaglandin E
GO:0035757 chemokine (C-C motif) ligand 19 binding
GO:0035758 chemokine (C-C motif) ligand 21 binding
GO:0038117 C-C motif chemokine 19 receptor activity
GO:0038121 C-C motif chemokine 21 receptor activity
GO:0042102 positive regulation of T cell proliferation
GO:0043547 positive regulation of GTPase activity
GO:0045060 negative thymic T cell selection
GO:0045627 positive regulation of T-helper 1 cell differentiation
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0048535 lymph node development
GO:0048872 homeostasis of number of cells
GO:0050766 positive regulation of phagocytosis
GO:0050862 positive regulation of T cell receptor signaling pathway
GO:0051491 positive regulation of filopodium assembly
GO:0060326 cell chemotaxis
GO:0071345 cellular response to cytokine stimulus
GO:0071731 response to nitric oxide
GO:0090023 positive regulation of neutrophil chemotaxis
GO:0097022 lymphocyte migration into lymph node
GO:0097029 mature conventional dendritic cell differentiation
GO:2000107 negative regulation of leukocyte apoptotic process
GO:2000147 positive regulation of cell motility
GO:2000412 positive regulation of thymocyte migration
GO:2000510 positive regulation of dendritic cell chemotaxis
GO:2000522 positive regulation of immunological synapse formation
GO:2000525 positive regulation of T cell costimulation
GO:2000526 positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
GO:2000547 regulation of dendritic cell dendrite assembly

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000355 Chemokine receptor familyFamilyFamily
IPR001718 CC chemokine receptor 7FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CCR7_MOUSECD3Z_HUMANMINT22922463 details