Entity Details

Primary name VPS11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H270
EntryNameVPS11_HUMAN
FullNameVacuolar protein sorting-associated protein 11 homolog
TaxID9606
Evidenceevidence at protein level
Length941
SequenceStatuscomplete
DateCreated2002-09-19
DateModified2021-06-02

Ontological Relatives

GenesVPS11

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005776 autophagosome
GO:0006886 intracellular protein transport
GO:0006904 vesicle docking involved in exocytosis
GO:0006914 autophagy
GO:0007032 endosome organization
GO:0007033 vacuole organization
GO:0008333 endosome to lysosome transport
GO:0016567 protein ubiquitination
GO:0019904 protein domain specific binding
GO:0019905 syntaxin binding
GO:0030136 clathrin-coated vesicle
GO:0030139 endocytic vesicle
GO:0030674 protein-macromolecule adaptor activity
GO:0030897 HOPS complex
GO:0031647 regulation of protein stability
GO:0031902 late endosome membrane
GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway
GO:0034058 endosomal vesicle fusion
GO:0035542 regulation of SNARE complex assembly
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
GO:1902115 regulation of organelle assembly
GO:1903364 positive regulation of cellular protein catabolic process
GO:1903955 positive regulation of protein targeting to mitochondrion
GO:2000643 positive regulation of early endosome to late endosome transport

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle
Early endosome
Endosome
Late endosome membrane
Lysosome membrane

Domains

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DomainNameCategoryType
IPR000547 Clathrin, heavy chain/VPS, 7-fold repeatRepeatRepeat
IPR001841 Zinc finger, RING-typeDomainDomain
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR016528 Vacuolar protein sorting-associated protein 11FamilyFamily
IPR024763 Vacuolar protein sorting protein 11, C-terminalDomainDomain
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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