Entity Details

Primary name TNKS2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H2K2
EntryNameTNKS2_HUMAN
FullNamePoly [ADP-ribose] polymerase tankyrase-2
TaxID9606
Evidenceevidence at protein level
Length1166
SequenceStatuscomplete
DateCreated2002-03-27
DateModified2021-06-02

Ontological Relatives

GenesTNKS2

GO terms

Show/Hide Table
GOName
GO:0000139 Golgi membrane
GO:0000209 protein polyubiquitination
GO:0000242 pericentriolar material
GO:0000781 chromosome, telomeric region
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006471 protein ADP-ribosylation
GO:0016055 Wnt signaling pathway
GO:0019899 enzyme binding
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0035264 multicellular organism growth
GO:0040014 regulation of multicellular organism growth
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0070198 protein localization to chromosome, telomeric region
GO:0070212 protein poly-ADP-ribosylation
GO:0070213 protein auto-ADP-ribosylation
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1904355 positive regulation of telomere capping
GO:1904357 negative regulation of telomere maintenance via telomere lengthening
GO:1990404 protein ADP-ribosylase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Chromosome
Cytoplasm
Golgi apparatus membrane
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001660 Sterile alpha motif domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR012317 Poly(ADP-ribose) polymerase, catalytic domainDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

4 interactions