Entity Details - PICKLE: A Protein InteraCtion KnowLedgebasE

Accession	P47877
EntryName	IBP2_MOUSE
FullName	Insulin-like growth factor-binding protein 2
TaxID	10090
Evidence	evidence at transcript level
Length	305
SequenceStatus	complete
DateCreated	1996-02-01
DateModified	2021-06-02

Genes

Igfbp2

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GO	Name
GO:0005520	insulin-like growth factor binding
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0007165	signal transduction
GO:0007565	female pregnancy
GO:0007568	aging
GO:0007584	response to nutrient
GO:0009612	response to mechanical stimulus
GO:0010226	response to lithium ion
GO:0016324	apical plasma membrane
GO:0031410	cytoplasmic vesicle
GO:0031994	insulin-like growth factor I binding
GO:0031995	insulin-like growth factor II binding
GO:0032355	response to estradiol
GO:0032526	response to retinoic acid
GO:0032870	cellular response to hormone stimulus
GO:0040008	regulation of growth
GO:0042104	positive regulation of activated T cell proliferation
GO:0042493	response to drug
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
GO:0043627	response to estrogen
GO:0051384	response to glucocorticoid

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Subcellular Location
Secreted

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Domain	Name	Category	Type
IPR000716	Thyroglobulin type-1	Domain	Domain
IPR000867	Insulin-like growth factor-binding protein, IGFBP	Domain	Domain
IPR009030	Growth factor receptor cysteine-rich domain superfamily	Family	Homologous superfamily
IPR012210	Insulin-like growth factor binding protein 2	Family	Family
IPR017891	Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site	Site	Conserved site
IPR022321	Insulin-like growth factor-binding protein family 1-6, chordata	Family	Family
IPR036857	Thyroglobulin type-1 superfamily	Family	Homologous superfamily

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2 interactions

Interactor	Partner	Sources	Publications	Link
IBP2_MOUSE	FZD8_MOUSE	DIP	18528331	details
IBP2_MOUSE	LRP6_HUMAN	DIP	18528331	details