Entity Details

Primary name IBP3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP47878
EntryNameIBP3_MOUSE
FullNameInsulin-like growth factor-binding protein 3
TaxID10090
Evidenceevidence at transcript level
Length292
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesIgfbp3

GO terms

Show/Hide Table
GOName
GO:0000792 heterochromatin
GO:0001558 regulation of cell growth
GO:0001649 osteoblast differentiation
GO:0001933 negative regulation of protein phosphorylation
GO:0001968 fibronectin binding
GO:0005520 insulin-like growth factor binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0006468 protein phosphorylation
GO:0008160 protein tyrosine phosphatase activator activity
GO:0008285 negative regulation of cell population proliferation
GO:0010666 positive regulation of cardiac muscle cell apoptotic process
GO:0010906 regulation of glucose metabolic process
GO:0014912 negative regulation of smooth muscle cell migration
GO:0031091 platelet alpha granule
GO:0031994 insulin-like growth factor I binding
GO:0031995 insulin-like growth factor II binding
GO:0040008 regulation of growth
GO:0042567 insulin-like growth factor ternary complex
GO:0042568 insulin-like growth factor binary complex
GO:0043065 positive regulation of apoptotic process
GO:0043410 positive regulation of MAPK cascade
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway
GO:0044342 type B pancreatic cell proliferation
GO:0045663 positive regulation of myoblast differentiation
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:1902512 positive regulation of apoptotic DNA fragmentation
GO:2000844 negative regulation of testosterone secretion

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR000716 Thyroglobulin type-1DomainDomain
IPR000867 Insulin-like growth factor-binding protein, IGFBPDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR012211 Insulin-like growth factor binding protein 3FamilyFamily
IPR017891 Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved siteSiteConserved site
IPR022321 Insulin-like growth factor-binding protein family 1-6, chordataFamilyFamily
IPR036857 Thyroglobulin type-1 superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
IBP3_MOUSEDUX4_HUMANBioGRID, IntAct26816005 details