Entity Details

Primary name ECT2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H8V3
EntryNameECT2_HUMAN
FullNameProtein ECT2
TaxID9606
Evidenceevidence at protein level
Length914
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesECT2

GO terms

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GOName
GO:0000281 mitotic cytokinesis
GO:0000902 cell morphogenesis
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005911 cell-cell junction
GO:0005923 bicellular tight junction
GO:0005938 cell cortex
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007399 nervous system development
GO:0015031 protein transport
GO:0016604 nuclear body
GO:0030154 cell differentiation
GO:0030496 midbody
GO:0031267 small GTPase binding
GO:0032147 activation of protein kinase activity
GO:0032154 cleavage furrow
GO:0032467 positive regulation of cytokinesis
GO:0035556 intracellular signal transduction
GO:0042307 positive regulation of protein import into nucleus
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043547 positive regulation of GTPase activity
GO:0045666 positive regulation of neuron differentiation
GO:0045859 regulation of protein kinase activity
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0051260 protein homooligomerization
GO:0051988 regulation of attachment of spindle microtubules to kinetochore
GO:0070301 cellular response to hydrogen peroxide
GO:0070830 bicellular tight junction assembly
GO:0071277 cellular response to calcium ion
GO:0071479 cellular response to ionizing radiation
GO:0072686 mitotic spindle
GO:0090630 activation of GTPase activity
GO:0097149 centralspindlin complex
GO:2000431 regulation of cytokinesis, actomyosin contractile ring assembly

Subcellular Location

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Subcellular Location
Cell junction
Cleavage furrow
Cytoplasm
Midbody
Nucleus

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved siteSiteConserved site
IPR001357 BRCT domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR026817 Guanine nucleotide exchange factor Ect2FamilyFamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036420 BRCT domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink