Entity Details

Primary name TEAD2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP48301
EntryNameTEAD2_MOUSE
FullNameTranscriptional enhancer factor TEF-4
TaxID10090
Evidenceevidence at transcript level
Length445
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesTead2

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001223 transcription coactivator binding
GO:0001570 vasculogenesis
GO:0001843 neural tube closure
GO:0003143 embryonic heart tube morphogenesis
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0030903 notochord development
GO:0035329 hippo signaling
GO:0043231 intracellular membrane-bounded organelle
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048339 paraxial mesoderm development
GO:0048368 lateral mesoderm development
GO:0048568 embryonic organ development
GO:0060548 negative regulation of cell death
GO:0065003 protein-containing complex assembly
GO:0071300 cellular response to retinoic acid
GO:0097718 disordered domain specific binding
GO:0140552 TEAD-YAP complex
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000736 regulation of stem cell differentiation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000818 TEA/ATTS domainDomainDomain
IPR016361 Transcriptional enhancer factor, metazoaFamilyFamily
IPR038096 TEA/ATTS domain superfamilyFamilyHomologous superfamily
IPR041086 YAP binding domainDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
TEAD2_MOUSEWWTR1_MOUSEBioGRID, IntAct20211142 details
TEAD2_MOUSEYAP1_MOUSEBioGRID11358867 details
TEAD2_MOUSEMPDZ_MOUSEBioGRID11358867 details