Entity Details

Primary name GA45A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP48316
EntryNameGA45A_MOUSE
FullNameGrowth arrest and DNA damage-inducible protein GADD45 alpha
TaxID10090
Evidenceevidence at protein level
Length165
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesGadd45a

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000185 obsolete activation of MAPKKK activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006469 negative regulation of protein kinase activity
GO:0007098 centrosome cycle
GO:0016525 negative regulation of angiogenesis
GO:0016607 nuclear speck
GO:0019900 kinase binding
GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein
GO:0042770 signal transduction in response to DNA damage
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043537 negative regulation of blood vessel endothelial cell migration
GO:0046330 positive regulation of JNK cascade
GO:0046982 protein heterodimerization activity
GO:0047485 protein N-terminus binding
GO:0051726 regulation of cell cycle
GO:0071260 cellular response to mechanical stimulus
GO:0071479 cellular response to ionizing radiation
GO:0071901 negative regulation of protein serine/threonine kinase activity
GO:1900745 positive regulation of p38MAPK cascade
GO:1990841 promoter-specific chromatin binding
GO:2000379 positive regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45DomainDomain
IPR024824 Growth arrest and DNA damage-inducible protein GADD45FamilyFamily
IPR029064 50S ribosomal protein L30e-likeFamilyHomologous superfamily

Diseases

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