Entity Details

Primary name RFX3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP48381
EntryNameRFX3_MOUSE
FullNameTranscription factor RFX3
TaxID10090
Evidenceevidence at protein level
Length749
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesRfx3

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007368 determination of left/right symmetry
GO:0031018 endocrine pancreas development
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048469 cell maturation
GO:0050796 regulation of insulin secretion
GO:0060271 cilium assembly
GO:0060285 cilium-dependent cell motility
GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry
GO:0072560 type B pancreatic cell maturation
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000078 positive regulation of type B pancreatic cell development

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003150 DNA-binding RFX-type winged-helix domainDomainDomain
IPR007668 RFX1 transcription activation regionDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR039779 RFX-like DNA-binding proteinFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
RFX3_MOUSEGPS2_MOUSEBioGRID18218630 details