Entity Details

Primary name CBX8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HC52
EntryNameCBX8_HUMAN
FullNameChromobox protein homolog 8
TaxID9606
Evidenceevidence at protein level
Length389
SequenceStatuscomplete
DateCreated2001-08-29
DateModified2021-06-02

Ontological Relatives

GenesCBX8

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000792 heterochromatin
GO:0003727 single-stranded RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0008284 positive regulation of cell population proliferation
GO:0016574 histone ubiquitination
GO:0031519 PcG protein complex
GO:0032967 positive regulation of collagen biosynthetic process
GO:0035064 methylated histone binding
GO:0035102 PRC1 complex
GO:0045739 positive regulation of DNA repair
GO:0070301 cellular response to hydrogen peroxide
GO:0097027 ubiquitin-protein transferase activator activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000953 Chromo/chromo shadow domainDomainDomain
IPR016197 Chromo-like domain superfamilyFamilyHomologous superfamily
IPR023779 Chromo domain, conserved siteSiteConserved site
IPR023780 Chromo domainDomainDomain
IPR033773 CBX family C-terminal motifSiteConserved site

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CBX8_HUMANAF9_MOUSEDIP23260655 details