Entity Details

Primary name GDNF_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP48540
EntryNameGDNF_MOUSE
FullNameGlial cell line-derived neurotrophic factor
TaxID10090
Evidenceevidence at protein level
Length211
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesGdnf

GO terms

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GOName
GO:0001656 metanephros development
GO:0001657 ureteric bud development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001755 neural crest cell migration
GO:0001759 organ induction
GO:0001941 postsynaptic membrane organization
GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0005160 transforming growth factor beta receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007399 nervous system development
GO:0007422 peripheral nervous system development
GO:0008083 growth factor activity
GO:0008283 cell population proliferation
GO:0008284 positive regulation of cell population proliferation
GO:0009611 response to wounding
GO:0010468 regulation of gene expression
GO:0021516 dorsal spinal cord development
GO:0021784 postganglionic parasympathetic fiber development
GO:0030116 glial cell-derived neurotrophic factor receptor binding
GO:0030182 neuron differentiation
GO:0030432 peristalsis
GO:0030971 receptor tyrosine kinase binding
GO:0031175 neuron projection development
GO:0032770 positive regulation of monooxygenase activity
GO:0042803 protein homodimerization activity
GO:0043235 receptor complex
GO:0043524 negative regulation of neuron apoptotic process
GO:0045597 positive regulation of cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048018 receptor ligand activity
GO:0048255 mRNA stabilization
GO:0048484 enteric nervous system development
GO:0048485 sympathetic nervous system development
GO:0048568 embryonic organ development
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051584 regulation of dopamine uptake involved in synaptic transmission
GO:0060676 ureteric bud formation
GO:0060688 regulation of morphogenesis of a branching structure
GO:0071549 cellular response to dexamethasone stimulus
GO:0071679 commissural neuron axon guidance
GO:0072106 regulation of ureteric bud formation
GO:0072107 positive regulation of ureteric bud formation
GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis
GO:1901166 neural crest cell migration involved in autonomic nervous system development
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001260 regulation of semaphorin-plexin signaling pathway

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001839 Transforming growth factor-beta, C-terminalDomainDomain
IPR016649 Glial cell line-derived neurotrophic factorFamilyFamily
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily
IPR043401 Glial cell line-derived neurotrophic factor familyFamilyFamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink