Entity Details

Primary name BRD7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NPI1
EntryNameBRD7_HUMAN
FullNameBromodomain-containing protein 7
TaxID9606
Evidenceevidence at protein level
Length651
SequenceStatuscomplete
DateCreated2006-03-21
DateModified2021-06-02

Ontological Relatives

GenesBRD7

GO terms

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GOName
GO:0000976 transcription cis-regulatory region binding
GO:0002039 p53 binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007049 cell cycle
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0016055 Wnt signaling pathway
GO:0035066 positive regulation of histone acetylation
GO:0042393 histone binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0070577 lysine-acetylated histone binding
GO:1901796 regulation of signal transduction by p53 class mediator
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001487 BromodomainDomainDomain
IPR021900 Protein of unknown function DUF3512FamilyFamily
IPR036427 Bromodomain-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
BRD7_HUMANPTN13_MOUSEMINT10526152 details
BRD7_HUMANDVL1_MOUSEBioGRID12941796 details