Entity Details

Primary name ATOH1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP48985
EntryNameATOH1_MOUSE
FullNameProtein atonal homolog 1
TaxID10090
Evidenceevidence at protein level
Length351
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesAtoh1

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001764 neuron migration
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007219 Notch signaling pathway
GO:0007411 axon guidance
GO:0007420 brain development
GO:0021987 cerebral cortex development
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0031490 chromatin DNA binding
GO:0042472 inner ear morphogenesis
GO:0042491 inner ear auditory receptor cell differentiation
GO:0042667 auditory receptor cell fate specification
GO:0042668 auditory receptor cell fate determination
GO:0043066 negative regulation of apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045609 positive regulation of inner ear auditory receptor cell differentiation
GO:0045664 regulation of neuron differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0048839 inner ear development
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000982 positive regulation of inner ear receptor cell differentiation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR032661 Protein atonal homologue 1FamilyFamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ATOH1_MOUSEMTG8_MOUSEBioGRID, IntAct20211142 details
ATOH1_MOUSETFE2_MOUSEDIP17878293 details