Entity Details

Primary name DDX21_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NR30
EntryNameDDX21_HUMAN
FullNameNucleolar RNA helicase 2
TaxID9606
Evidenceevidence at protein level
Length783
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesDDX21

GO terms

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GOName
GO:0001649 osteoblast differentiation
GO:0002735 positive regulation of myeloid dendritic cell cytokine production
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006364 rRNA processing
GO:0006366 transcription by RNA polymerase II
GO:0016020 membrane
GO:0019843 rRNA binding
GO:0030515 snoRNA binding
GO:0035198 miRNA binding
GO:0042802 identical protein binding
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330 response to exogenous dsRNA
GO:0045087 innate immune response
GO:0045815 positive regulation of gene expression, epigenetic
GO:0051607 defense response to virus
GO:0062176 R-loop disassembly
GO:0097322 7SK snRNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR001650 Helicase, C-terminalDomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR012562 GUCTDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR014014 RNA helicase, DEAD-box type, Q motifDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DDX21_HUMANRRP1B_MOUSEBioGRID19710015 details