Entity Details

Primary name ERCC3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP49135
EntryNameERCC3_MOUSE
FullNameGeneral transcription and DNA repair factor IIH helicase subunit XPB
TaxID10090
Evidenceevidence at transcript level
Length783
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesErcc3

GO terms

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GOName
GO:0000112 nucleotide-excision repair factor 3 complex
GO:0000439 transcription factor TFIIH core complex
GO:0000717 nucleotide-excision repair, DNA duplex unwinding
GO:0001666 response to hypoxia
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005669 transcription factor TFIID complex
GO:0005675 transcription factor TFIIH holo complex
GO:0006265 DNA topological change
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006289 nucleotide-excision repair
GO:0006362 transcription elongation from RNA polymerase I promoter
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006915 apoptotic process
GO:0006979 response to oxidative stress
GO:0008022 protein C-terminus binding
GO:0008104 protein localization
GO:0008134 transcription factor binding
GO:0009411 response to UV
GO:0009650 UV protection
GO:0016887 ATP hydrolysis activity
GO:0033683 nucleotide-excision repair, DNA incision
GO:0035315 hair cell differentiation
GO:0043065 positive regulation of apoptotic process
GO:0043138 3'-5' DNA helicase activity
GO:0047485 protein N-terminus binding
GO:0048568 embryonic organ development
GO:0097550 transcription preinitiation complex
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1990841 promoter-specific chromatin binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001161 Helicase XPB/Ssl2FamilyFamily
IPR001650 Helicase, C-terminalDomainDomain
IPR006935 Helicase/UvrB, N-terminalDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domainDomainDomain
IPR032830 Helicase XPB/Ssl2, N-terminal domainDomainDomain

Diseases

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Interactions

4 interactions