Entity Details

Primary name HELLS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NRZ9
EntryNameHELLS_HUMAN
FullNameLymphoid-specific helicase
TaxID9606
Evidenceevidence at protein level
Length838
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesHELLS

GO terms

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GOName
GO:0000775 chromosome, centromeric region
GO:0003682 chromatin binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005721 pericentric heterochromatin
GO:0006306 DNA methylation
GO:0006346 DNA methylation-dependent heterochromatin assembly
GO:0007049 cell cycle
GO:0007275 multicellular organism development
GO:0010216 maintenance of DNA methylation
GO:0016787 hydrolase activity
GO:0031508 pericentric heterochromatin assembly
GO:0046651 lymphocyte proliferation
GO:0051301 cell division
GO:0070615 nucleosome-dependent ATPase activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000330 SNF2, N-terminalDomainDomain
IPR001650 Helicase, C-terminalDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR038718 SNF2-like, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink