Entity Details

Primary name CISH_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NSE2
EntryNameCISH_HUMAN
FullNameCytokine-inducible SH2-containing protein
TaxID9606
Evidenceevidence at protein level
Length258
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesCISH

GO terms

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GOName
GO:0001558 regulation of cell growth
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005942 phosphatidylinositol 3-kinase complex
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0009968 negative regulation of signal transduction
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
GO:0038111 interleukin-7-mediated signaling pathway
GO:0043687 post-translational protein modification
GO:0046854 phosphatidylinositol phosphate biosynthetic process
GO:0046935 1-phosphatidylinositol-3-kinase regulator activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR001496 SOCS box domainDomainDomain
IPR028425 Cytokine-inducible SH2-containing proteinFamilyFamily
IPR035887 CIS, SH2 domainDomainDomain
IPR036036 SOCS box-like domain superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CISH_HUMANEPOR_MOUSEMINT9774439 details