Entity Details

Primary name PPM1A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP49443
EntryNamePPM1A_MOUSE
FullNameProtein phosphatase 1A
TaxID10090
Evidenceevidence at protein level
Length382
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesPpm1a

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006470 protein dephosphorylation
GO:0006499 N-terminal protein myristoylation
GO:0008022 protein C-terminus binding
GO:0010991 negative regulation of SMAD protein complex assembly
GO:0016020 membrane
GO:0016311 dephosphorylation
GO:0030145 manganese ion binding
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0033192 calmodulin-dependent protein phosphatase activity
GO:0035970 peptidyl-threonine dephosphorylation
GO:0043005 neuron projection
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044325 transmembrane transporter binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046827 positive regulation of protein export from nucleus
GO:0070412 R-SMAD binding
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:1901223 negative regulation of NIK/NF-kappaB signaling

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000222 PPM-type phosphatase, divalent cation bindingSiteBinding site
IPR001932 PPM-type phosphatase domainDomainDomain
IPR012911 Protein serine/threonine phosphatase 2C, C-terminalDomainDomain
IPR036457 PPM-type phosphatase domain superfamilyFamilyHomologous superfamily
IPR036580 Phosphatase 2C, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink