Entity Details

Primary name ACHA7_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP49582
EntryNameACHA7_MOUSE
FullNameNeuronal acetylcholine receptor subunit alpha-7
TaxID10090
Evidenceevidence at protein level
Length502
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesChrna7

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001540 amyloid-beta binding
GO:0001666 response to hypoxia
GO:0001933 negative regulation of protein phosphorylation
GO:0001934 positive regulation of protein phosphorylation
GO:0001988 positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
GO:0005216 ion channel activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005892 acetylcholine-gated channel complex
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0006897 endocytosis
GO:0007165 signal transduction
GO:0007268 chemical synaptic transmission
GO:0007271 synaptic transmission, cholinergic
GO:0007611 learning or memory
GO:0007613 memory
GO:0008179 adenylate cyclase binding
GO:0008284 positive regulation of cell population proliferation
GO:0008306 associative learning
GO:0009409 response to cold
GO:0009897 external side of plasma membrane
GO:0014061 regulation of norepinephrine secretion
GO:0014069 postsynaptic density
GO:0015464 acetylcholine receptor activity
GO:0015643 toxic substance binding
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0017081 chloride channel regulator activity
GO:0019228 neuronal action potential
GO:0019901 protein kinase binding
GO:0022848 acetylcholine-gated cation-selective channel activity
GO:0030317 flagellated sperm motility
GO:0030424 axon
GO:0030425 dendrite
GO:0030426 growth cone
GO:0030594 neurotransmitter receptor activity
GO:0030673 axolemma
GO:0032094 response to food
GO:0032222 regulation of synaptic transmission, cholinergic
GO:0032225 regulation of synaptic transmission, dopaminergic
GO:0032279 asymmetric synapse
GO:0032691 negative regulation of interleukin-1 beta production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034220 ion transmembrane transport
GO:0035094 response to nicotine
GO:0035095 behavioral response to nicotine
GO:0042110 T cell activation
GO:0042113 B cell activation
GO:0042166 acetylcholine binding
GO:0042391 regulation of membrane potential
GO:0042698 ovulation cycle
GO:0042734 presynaptic membrane
GO:0042803 protein homodimerization activity
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0043198 dendritic shaft
GO:0044853 plasma membrane raft
GO:0045121 membrane raft
GO:0045202 synapse
GO:0045471 response to ethanol
GO:0045766 positive regulation of angiogenesis
GO:0048149 behavioral response to ethanol
GO:0050727 regulation of inflammatory response
GO:0050728 negative regulation of inflammatory response
GO:0050804 modulation of chemical synaptic transmission
GO:0050808 synapse organization
GO:0050877 nervous system process
GO:0050890 cognition
GO:0050893 sensory processing
GO:0051117 ATPase binding
GO:0051247 positive regulation of protein metabolic process
GO:0051823 regulation of synapse structural plasticity
GO:0060112 generation of ovulation cycle rhythm
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0095500 acetylcholine receptor signaling pathway
GO:0097061 dendritic spine organization
GO:0097110 scaffold protein binding
GO:0098690 glycinergic synapse
GO:0098793 presynapse
GO:0098815 modulation of excitatory postsynaptic potential
GO:0098981 cholinergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:0099060 integral component of postsynaptic specialization membrane
GO:0099065 integral component of spine apparatus membrane
GO:0140059 dendrite arborization
GO:1900273 positive regulation of long-term synaptic potentiation
GO:1901214 regulation of neuron death
GO:1902004 positive regulation of amyloid-beta formation
GO:1902430 negative regulation of amyloid-beta formation
GO:1902991 regulation of amyloid precursor protein catabolic process
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
GO:1904645 response to amyloid-beta
GO:1905144 response to acetylcholine
GO:1905906 regulation of amyloid fibril formation
GO:1905920 positive regulation of CoA-transferase activity
GO:1905923 positive regulation of acetylcholine biosynthetic process
GO:2000300 regulation of synaptic vesicle exocytosis
GO:2000463 positive regulation of excitatory postsynaptic potential

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR002394 Nicotinic acetylcholine receptorFamilyFamily
IPR006029 Neurotransmitter-gated ion-channel transmembrane domainDomainDomain
IPR006201 Neurotransmitter-gated ion-channelFamilyFamily
IPR006202 Neurotransmitter-gated ion-channel ligand-binding domainDomainDomain
IPR018000 Neurotransmitter-gated ion-channel, conserved siteSiteConserved site
IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamilyFamilyHomologous superfamily
IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions