Entity Details

Primary name POTE1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NUX5
EntryNamePOTE1_HUMAN
FullNameProtection of telomeres protein 1
TaxID9606
Evidenceevidence at protein level
Length634
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesPOT1

GO terms

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GOName
GO:0000723 telomere maintenance
GO:0000781 chromosome, telomeric region
GO:0000783 nuclear telomere cap complex
GO:0005654 nucleoplasm
GO:0007004 telomere maintenance via telomerase
GO:0010521 telomerase inhibitor activity
GO:0016233 telomere capping
GO:0017151 DEAD/H-box RNA helicase binding
GO:0032201 telomere maintenance via semi-conservative replication
GO:0032202 telomere assembly
GO:0032210 regulation of telomere maintenance via telomerase
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0032508 DNA duplex unwinding
GO:0042162 telomeric DNA binding
GO:0043047 single-stranded telomeric DNA binding
GO:0045007 depurination
GO:0048239 negative regulation of DNA recombination at telomere
GO:0051096 positive regulation of helicase activity
GO:0051973 positive regulation of telomerase activity
GO:0051974 negative regulation of telomerase activity
GO:0060383 positive regulation of DNA strand elongation
GO:0061820 telomeric D-loop disassembly
GO:0061821 telomeric D-loop binding
GO:0070187 shelterin complex
GO:0070200 establishment of protein localization to telomere
GO:0098505 G-rich strand telomeric DNA binding
GO:1900051 positive regulation of histone exchange
GO:1905773 8-hydroxy-2'-deoxyguanosine DNA binding
GO:1905774 regulation of DNA helicase activity
GO:1905776 positive regulation of DNA helicase activity
GO:1990955 G-rich single-stranded DNA binding
GO:2001032 regulation of double-strand break repair via nonhomologous end joining

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR011564 Telomeric single stranded DNA binding POT1/Cdc13DomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR028389 Protection of telomeres protein 1FamilyFamily
IPR032042 Protection of telomeres protein 1, ssDNA-binding domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
POTE1_HUMANACD_MOUSEDIP17632522 details