Entity Details

Primary name HCLS1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP49710
EntryNameHCLS1_MOUSE
FullNameHematopoietic lineage cell-specific protein
TaxID10090
Evidenceevidence at protein level
Length486
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesHcls1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0008284 positive regulation of cell population proliferation
GO:0009725 response to hormone
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0017124 SH3 domain binding
GO:0019901 protein kinase binding
GO:0030041 actin filament polymerization
GO:0030218 erythrocyte differentiation
GO:0030427 site of polarized growth
GO:0030833 regulation of actin filament polymerization
GO:0030854 positive regulation of granulocyte differentiation
GO:0030864 cortical actin cytoskeleton
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0042307 positive regulation of protein import into nucleus
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0044877 protein-containing complex binding
GO:0045651 positive regulation of macrophage differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051015 actin filament binding
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051897 positive regulation of protein kinase B signaling
GO:0071345 cellular response to cytokine stimulus
GO:2000107 negative regulation of leukocyte apoptotic process

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR003134 Hs1/CortactinRepeatRepeat
IPR028534 Hematopoietic lineage cell-specific proteinFamilyFamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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