Entity Details

Primary name CAV1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP49817
EntryNameCAV1_MOUSE
FullNameCaveolin-1
TaxID10090
Evidenceevidence at protein level
Length178
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCav1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000139 Golgi membrane
GO:0000149 SNARE binding
GO:0000188 obsolete inactivation of MAPK activity
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0001666 response to hypoxia
GO:0001937 negative regulation of endothelial cell proliferation
GO:0001938 positive regulation of endothelial cell proliferation
GO:0001960 negative regulation of cytokine-mediated signaling pathway
GO:0002026 regulation of the force of heart contraction
GO:0002080 acrosomal membrane
GO:0002095 caveolar macromolecular signaling complex
GO:0002931 response to ischemia
GO:0003057 regulation of the force of heart contraction by chemical signal
GO:0005102 signaling receptor binding
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005768 endosome
GO:0005778 peroxisomal membrane
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005901 caveola
GO:0005925 focal adhesion
GO:0005929 cilium
GO:0005938 cell cortex
GO:0006641 triglyceride metabolic process
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0006897 endocytosis
GO:0006940 regulation of smooth muscle contraction
GO:0007519 skeletal muscle tissue development
GO:0007595 lactation
GO:0008104 protein localization
GO:0008285 negative regulation of cell population proliferation
GO:0009612 response to mechanical stimulus
GO:0009617 response to bacterium
GO:0009925 basal plasma membrane
GO:0009967 positive regulation of signal transduction
GO:0009968 negative regulation of signal transduction
GO:0009986 cell surface
GO:0010524 positive regulation of calcium ion transport into cytosol
GO:0010608 posttranscriptional regulation of gene expression
GO:0010628 positive regulation of gene expression
GO:0010656 negative regulation of muscle cell apoptotic process
GO:0010875 positive regulation of cholesterol efflux
GO:0015031 protein transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016504 peptidase activator activity
GO:0019065 receptor-mediated endocytosis of virus by host cell
GO:0019217 regulation of fatty acid metabolic process
GO:0019899 enzyme binding
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0019905 syntaxin binding
GO:0019915 lipid storage
GO:0030154 cell differentiation
GO:0030193 regulation of blood coagulation
GO:0030335 positive regulation of cell migration
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0030674 protein-macromolecule adaptor activity
GO:0030857 negative regulation of epithelial cell differentiation
GO:0030879 mammary gland development
GO:0031116 positive regulation of microtubule polymerization
GO:0031267 small GTPase binding
GO:0031295 T cell costimulation
GO:0031397 negative regulation of protein ubiquitination
GO:0031398 positive regulation of protein ubiquitination
GO:0031410 cytoplasmic vesicle
GO:0031623 receptor internalization
GO:0032091 negative regulation of protein binding
GO:0032092 positive regulation of protein binding
GO:0032507 maintenance of protein location in cell
GO:0032570 response to progesterone
GO:0032991 protein-containing complex
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0033344 cholesterol efflux
GO:0033484 nitric oxide homeostasis
GO:0033612 receptor serine/threonine kinase binding
GO:0034141 positive regulation of toll-like receptor 3 signaling pathway
GO:0038016 insulin receptor internalization
GO:0042060 wound healing
GO:0042310 vasoconstriction
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein
GO:0042632 cholesterol homeostasis
GO:0042802 identical protein binding
GO:0043085 positive regulation of catalytic activity
GO:0043407 negative regulation of MAP kinase activity
GO:0043409 negative regulation of MAPK cascade
GO:0043627 response to estrogen
GO:0044325 transmembrane transporter binding
GO:0044877 protein-containing complex binding
GO:0045019 negative regulation of nitric oxide biosynthetic process
GO:0045121 membrane raft
GO:0045665 negative regulation of neuron differentiation
GO:0045807 positive regulation of endocytosis
GO:0045907 positive regulation of vasoconstriction
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT
GO:0046785 microtubule polymerization
GO:0046982 protein heterodimerization activity
GO:0048471 perinuclear region of cytoplasm
GO:0048550 negative regulation of pinocytosis
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0050998 nitric-oxide synthase binding
GO:0051001 negative regulation of nitric-oxide synthase activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051117 ATPase binding
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0051592 response to calcium ion
GO:0051899 membrane depolarization
GO:0052547 regulation of peptidase activity
GO:0055074 calcium ion homeostasis
GO:0060056 mammary gland involution
GO:0060090 molecular adaptor activity
GO:0060355 positive regulation of cell adhesion molecule production
GO:0060546 negative regulation of necroptotic process
GO:0061099 negative regulation of protein tyrosine kinase activity
GO:0070320 inward rectifier potassium channel inhibitor activity
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0070836 caveola assembly
GO:0071260 cellular response to mechanical stimulus
GO:0071360 cellular response to exogenous dsRNA
GO:0071375 cellular response to peptide hormone stimulus
GO:0071455 cellular response to hyperoxia
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0071711 basement membrane organization
GO:0072584 caveolin-mediated endocytosis
GO:0086091 regulation of heart rate by cardiac conduction
GO:0086098 angiotensin-activated signaling pathway involved in heart process
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0090398 cellular senescence
GO:0097190 apoptotic signaling pathway
GO:0098903 regulation of membrane repolarization during action potential
GO:0098911 regulation of ventricular cardiac muscle cell action potential
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1900027 regulation of ruffle assembly
GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation
GO:1901380 negative regulation of potassium ion transmembrane transport
GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction
GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:1903598 positive regulation of gap junction assembly
GO:1903609 negative regulation of inward rectifier potassium channel activity
GO:2000286 receptor internalization involved in canonical Wnt signaling pathway
GO:2000535 regulation of entry of bacterium into host cell
GO:2000811 negative regulation of anoikis
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway
GO:2001258 negative regulation of cation channel activity

Subcellular Location

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Subcellular Location
Cell membrane
Golgi apparatus
Golgi apparatus membrane
Membrane
Membrane raft

Domains

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DomainNameCategoryType
IPR001612 CaveolinFamilyFamily
IPR015504 Caveolin-1FamilyFamily
IPR018361 Caveolin, conserved siteSiteConserved site

Diseases

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