Entity Details

Primary name TAB2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NYJ8
EntryNameTAB2_HUMAN
FullNameTGF-beta-activated kinase 1 and MAP3K7-binding protein 2
TaxID9606
Evidenceevidence at protein level
Length693
SequenceStatuscomplete
DateCreated2006-03-07
DateModified2021-06-02

Ontological Relatives

GenesTAB2

GO terms

Show/Hide Table
GOName
GO:0000187 obsolete activation of MAPK activity
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002753 cytoplasmic pattern recognition receptor signaling pathway
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0007254 JNK cascade
GO:0007507 heart development
GO:0008270 zinc ion binding
GO:0010008 endosome membrane
GO:0010507 negative regulation of autophagy
GO:0032496 response to lipopolysaccharide
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 ubiquitin binding
GO:0045860 positive regulation of protein kinase activity
GO:0050852 T cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR001876 Zinc finger, RanBP2-typeDomainDomain
IPR003892 Ubiquitin system component CUEDomainDomain
IPR036443 Zinc finger, RanBP2-type superfamilyFamilyHomologous superfamily
IPR041911 TAB2/3, CUE domainDomainDomain

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TAB2_HUMANM3K7_MOUSEBioGRID, DIP, IntAct10882101 17158449 19675569 details
TAB2_HUMANTR30A_MOUSEBioGRID18345001 details