Entity Details

Primary name DHI1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP50172
EntryNameDHI1_MOUSE
FullNameCorticosteroid 11-beta-dehydrogenase isozyme 1
TaxID10090
Evidenceevidence at protein level
Length292
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesHsd11b1

GO terms

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GOName
GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity
GO:0005496 steroid binding
GO:0005737 cytoplasm
GO:0005791 rough endoplasmic reticulum
GO:0006704 glucocorticoid biosynthetic process
GO:0006706 steroid catabolic process
GO:0006713 glucocorticoid catabolic process
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030324 lung development
GO:0031965 nuclear membrane
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0043456 regulation of pentose-phosphate shunt
GO:0045177 apical part of cell
GO:0050661 NADP binding
GO:0070524 11-beta-hydroxysteroid dehydrogenase (NADP+) activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR020904 Short-chain dehydrogenase/reductase, conserved siteSiteConserved site
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DHI1_MOUSECP2DA_MOUSEIntAct21751364 details