Entity Details

Primary name LHX3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP50481
EntryNameLHX3_MOUSE
FullNameLIM/homeobox protein Lhx3
TaxID10090
Evidenceevidence at protein level
Length400
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesLhx3

GO terms

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GOName
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001890 placenta development
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008045 motor neuron axon guidance
GO:0009953 dorsal/ventral pattern formation
GO:0021520 spinal cord motor neuron cell fate specification
GO:0021521 ventral spinal cord interneuron specification
GO:0021526 medial motor column neuron differentiation
GO:0021527 spinal cord association neuron differentiation
GO:0021983 pituitary gland development
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0030324 lung development
GO:0043066 negative regulation of apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048839 inner ear development

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR001781 Zinc finger, LIM-typeDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
LHX3_MOUSEISL1_MOUSEMINT18583962 details
LHX3_MOUSELDB1_MOUSEMINT18583962 details