Entity Details

Primary name ASH2L_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UBL3
EntryNameASH2L_HUMAN
FullNameSet1/Ash2 histone methyltransferase complex subunit ASH2
TaxID9606
Evidenceevidence at protein level
Length628
SequenceStatuscomplete
DateCreated2003-06-16
DateModified2021-06-02

Ontological Relatives

GenesASH2L

GO terms

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GOName
GO:0000976 transcription cis-regulatory region binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006974 cellular response to DNA damage stimulus
GO:0008013 beta-catenin binding
GO:0008284 positive regulation of cell population proliferation
GO:0030097 hemopoiesis
GO:0035097 histone methyltransferase complex
GO:0043627 response to estrogen
GO:0044666 MLL3/4 complex
GO:0045652 regulation of megakaryocyte differentiation
GO:0046872 metal ion binding
GO:0048188 Set1C/COMPASS complex
GO:0051568 histone H3-K4 methylation
GO:1904837 beta-catenin-TCF complex assembly

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001870 B30.2/SPRY domainDomainDomain
IPR003877 SPRY domainDomainDomain
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR037353 Histone methyltransferase complex subunit ASH2FamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ASH2L_HUMANKMT2D_MOUSEIntAct16603732 details
ASH2L_HUMANCTNB1_MOUSEDIP22723415 details