Entity Details

Primary name MD2L2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UI95
EntryNameMD2L2_HUMAN
FullNameMitotic spindle assembly checkpoint protein MAD2B
TaxID9606
Evidenceevidence at protein level
Length211
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesMAD2L2

GO terms

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GOName
GO:0005829 cytosol
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0042772 DNA damage response, signal transduction resulting in transcription
GO:0045830 positive regulation of isotype switching
GO:0045893 positive regulation of transcription, DNA-templated
GO:0051301 cell division
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0042276 error-prone translesion synthesis
GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin
GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining
GO:0001558 regulation of cell growth
GO:0035861 site of double-strand break
GO:0042177 negative regulation of protein catabolic process
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0005654 nucleoplasm
GO:0005819 spindle
GO:0006302 double-strand break repair
GO:0007015 actin filament organization
GO:0008432 JUN kinase binding
GO:0010944 negative regulation of transcription by competitive promoter binding
GO:0016035 zeta DNA polymerase complex
GO:1904667 negative regulation of ubiquitin protein ligase activity
GO:2000042 negative regulation of double-strand break repair via homologous recombination
GO:2000678 negative regulation of transcription regulatory region DNA binding

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR003511 HORMA domainDomainDomain
IPR036570 HORMA domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
MD2L2_HUMANREV1_MOUSEBioGRID30963698 details