Entity Details

Primary name DRD4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP51436
EntryNameDRD4_MOUSE
FullNameD(4) dopamine receptor
TaxID10090
Evidenceevidence at protein level
Length387
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesDrd4

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go
GO:0001662 behavioral fear response
GO:0001963 synaptic transmission, dopaminergic
GO:0001975 response to amphetamine
GO:0004952 dopamine neurotransmitter receptor activity
GO:0004993 G protein-coupled serotonin receptor activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005938 cell cortex
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0007212 dopamine receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007614 short-term memory
GO:0008306 associative learning
GO:0008344 adult locomotory behavior
GO:0008355 olfactory learning
GO:0012506 vesicle membrane
GO:0016020 membrane
GO:0017124 SH3 domain binding
GO:0030424 axon
GO:0030425 dendrite
GO:0030594 neurotransmitter receptor activity
GO:0032417 positive regulation of sodium:proton antiporter activity
GO:0033674 positive regulation of kinase activity
GO:0034776 response to histamine
GO:0035240 dopamine binding
GO:0042053 regulation of dopamine metabolic process
GO:0042596 fear response
GO:0042752 regulation of circadian rhythm
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043195 terminal bouton
GO:0043197 dendritic spine
GO:0043679 axon terminus
GO:0046872 metal ion binding
GO:0046928 regulation of neurotransmitter secretion
GO:0048148 behavioral response to cocaine
GO:0048511 rhythmic process
GO:0050482 arachidonic acid secretion
GO:0050709 negative regulation of protein secretion
GO:0050805 negative regulation of synaptic transmission
GO:0050848 regulation of calcium-mediated signaling
GO:0051379 epinephrine binding
GO:0051380 norepinephrine binding
GO:0060080 inhibitory postsynaptic potential
GO:0060406 positive regulation of penile erection
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels
GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization
GO:1901386 negative regulation of voltage-gated calcium channel activity
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
GO:1904753 negative regulation of vascular associated smooth muscle cell migration
GO:2000300 regulation of synaptic vesicle exocytosis
GO:2000463 positive regulation of excitatory postsynaptic potential

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000929 Dopamine receptor familyFamilyFamily
IPR002185 Dopamine D4 receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

3 interactions