Entity Details

Primary name RORG_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP51450
EntryNameRORG_MOUSE
FullNameNuclear receptor ROR-gamma
TaxID10090
Evidenceevidence at protein level
Length516
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesRorc

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001223 transcription coactivator binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006468 protein phosphorylation
GO:0006805 xenobiotic metabolic process
GO:0008142 oxysterol binding
GO:0008270 zinc ion binding
GO:0009897 external side of plasma membrane
GO:0010906 regulation of glucose metabolic process
GO:0016604 nuclear body
GO:0019218 regulation of steroid metabolic process
GO:0030154 cell differentiation
GO:0032922 circadian regulation of gene expression
GO:0033077 T cell differentiation in thymus
GO:0036315 cellular response to sterol
GO:0042093 T-helper cell differentiation
GO:0042753 positive regulation of circadian rhythm
GO:0045586 regulation of gamma-delta T cell differentiation
GO:0045598 regulation of fat cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046632 alpha-beta T cell differentiation
GO:0048535 lymph node development
GO:0048537 mucosa-associated lymphoid tissue development
GO:0048541 Peyer's patch development
GO:0060612 adipose tissue development
GO:0070244 negative regulation of thymocyte apoptotic process
GO:0072539 T-helper 17 cell differentiation
GO:0098531 ligand-activated transcription factor activity
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR003079 Nuclear receptor RORFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily
IPR044101 Retinoid-related orphan receptors, DNA-binding domainDomainDomain

Diseases

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