Entity Details

Primary name CNTF_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP51642
EntryNameCNTF_MOUSE
FullNameCiliary neurotrophic factor
TaxID10090
Evidenceevidence at transcript level
Length198
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCntf

GO terms

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GOName
GO:0005125 cytokine activity
GO:0005127 ciliary neurotrophic factor receptor binding
GO:0005138 interleukin-6 receptor binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005829 cytosol
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0007399 nervous system development
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0030307 positive regulation of cell growth
GO:0030424 axon
GO:0032838 plasma membrane bounded cell projection cytoplasm
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0043025 neuronal cell body
GO:0043410 positive regulation of MAPK cascade
GO:0043524 negative regulation of neuron apoptotic process
GO:0044877 protein-containing complex binding
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0046533 negative regulation of photoreceptor cell differentiation
GO:0046668 regulation of retinal cell programmed cell death
GO:0046887 positive regulation of hormone secretion
GO:0048143 astrocyte activation
GO:0048644 muscle organ morphogenesis
GO:0048666 neuron development
GO:0048680 positive regulation of axon regeneration
GO:0048691 positive regulation of axon extension involved in regeneration
GO:0060075 regulation of resting membrane potential
GO:0060081 membrane hyperpolarization
GO:0070120 ciliary neurotrophic factor-mediated signaling pathway
GO:1901215 negative regulation of neuron death

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000151 Ciliary neurotrophic factor, CNTFFamilyFamily
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily

Diseases

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Interactions

3 interactions