Entity Details

Primary name FBW1B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UKB1
EntryNameFBW1B_HUMAN
FullNameF-box/WD repeat-containing protein 11
TaxID9606
Evidenceevidence at protein level
Length542
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesFBXW11

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000132 establishment of mitotic spindle orientation
GO:0000151 ubiquitin ligase complex
GO:0000209 protein polyubiquitination
GO:0000776 kinetochore
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005875 microtubule associated complex
GO:0005881 cytoplasmic microtubule
GO:0006470 protein dephosphorylation
GO:0007097 nuclear migration
GO:0007281 germ cell development
GO:0008090 retrograde axonal transport
GO:0016032 viral process
GO:0016055 Wnt signaling pathway
GO:0016567 protein ubiquitination
GO:0019005 SCF ubiquitin ligase complex
GO:0031023 microtubule organizing center organization
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031648 protein destabilization
GO:0038061 NIK/NF-kappaB signaling
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042753 positive regulation of circadian rhythm
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043687 post-translational protein modification
GO:0045862 positive regulation of proteolysis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046983 protein dimerization activity
GO:0047496 vesicle transport along microtubule
GO:0048511 rhythmic process
GO:0048854 brain morphogenesis
GO:0050852 T cell receptor signaling pathway
GO:0051010 microtubule plus-end binding
GO:0051403 stress-activated MAPK cascade
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070840 dynein complex binding
GO:1904115 axon cytoplasm
GO:2000574 obsolete regulation of microtubule motor activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR001810 F-box domainDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR020472 G-protein beta WD-40 repeatRepeatRepeat
IPR021977 D domain of beta-TrCPDomainDomain
IPR036047 F-box-like domain superfamilyFamilyHomologous superfamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions