Entity Details

Primary name DHB1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP51656
EntryNameDHB1_MOUSE
FullName17-beta-hydroxysteroid dehydrogenase type 1
TaxID10090
Evidenceevidence at protein level
Length344
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesHsd17b1

GO terms

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GOName
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0005496 steroid binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006703 estrogen biosynthetic process
GO:0030283 testosterone dehydrogenase [NAD(P)] activity
GO:0035410 dihydrotestosterone 17-beta-dehydrogenase activity
GO:0042803 protein homodimerization activity
GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity
GO:0047035 testosterone dehydrogenase (NAD+) activity
GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity
GO:0050661 NADP binding
GO:0060348 bone development
GO:0061370 testosterone biosynthetic process
GO:0070401 NADP+ binding
GO:0071248 cellular response to metal ion
GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity
GO:1903924 estradiol binding

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR011348 17beta-dehydrogenaseFamilyFamily
IPR020904 Short-chain dehydrogenase/reductase, conserved siteSiteConserved site
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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