Entity Details

Primary name NRX1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9ULB1
EntryNameNRX1A_HUMAN
FullNameNeurexin-1
TaxID9606
Evidenceevidence at protein level
Length1477
SequenceStatuscomplete
DateCreated2001-11-16
DateModified2021-06-02

Ontological Relatives

GenesNRXN1

GO terms

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GOName
GO:0005246 calcium channel regulator activity
GO:0005509 calcium ion binding
GO:0005730 nucleolus
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007158 neuron cell-cell adhesion
GO:0007268 chemical synaptic transmission
GO:0007269 neurotransmitter secretion
GO:0007411 axon guidance
GO:0007416 synapse assembly
GO:0007612 learning
GO:0009986 cell surface
GO:0030534 adult behavior
GO:0031965 nuclear membrane
GO:0031982 vesicle
GO:0033130 acetylcholine receptor binding
GO:0035176 social behavior
GO:0038023 signaling receptor activity
GO:0042297 vocal learning
GO:0042734 presynaptic membrane
GO:0042995 cell projection
GO:0043025 neuronal cell body
GO:0050839 cell adhesion molecule binding
GO:0050885 neuromuscular process controlling balance
GO:0051965 positive regulation of synapse assembly
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0071625 vocalization behavior
GO:0090129 positive regulation of synapse maturation
GO:0097104 postsynaptic membrane assembly
GO:0097109 neuroligin family protein binding
GO:0097116 gephyrin clustering involved in postsynaptic density assembly
GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly
GO:0097119 postsynaptic density protein 95 clustering
GO:2000463 positive regulation of excitatory postsynaptic potential

Subcellular Location

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Subcellular Location
Cell junction

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000742 EGF-like domainDomainDomain
IPR001791 Laminin G domainDomainDomain
IPR003585 Neurexin/syndecan/glycophorin CDomainDomain
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR027789 Syndecan/Neurexin domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB11093 Calcium citrateDrugbanksmall molecule
DB11348 Calcium PhosphateDrugbanksmall molecule
DB14481 Calcium phosphate dihydrateDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
NRX1A_HUMANNLGN1_MOUSEDIP18084303 details