Entity Details

Primary name CCR5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP51682
EntryNameCCR5_MOUSE
FullNameC-C chemokine receptor type 5
TaxID10090
Evidenceevidence at transcript level
Length354
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCcr5

GO terms

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GOName
GO:0003779 actin binding
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0006816 calcium ion transport
GO:0006952 defense response
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007267 cell-cell signaling
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0016021 integral component of membrane
GO:0016493 C-C chemokine receptor activity
GO:0019722 calcium-mediated signaling
GO:0019901 protein kinase binding
GO:0019957 C-C chemokine binding
GO:0022409 positive regulation of cell-cell adhesion
GO:0030336 negative regulation of cell migration
GO:0030517 negative regulation of axon extension
GO:0031622 positive regulation of fever generation
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0042802 identical protein binding
GO:0045666 positive regulation of neuron differentiation
GO:0050729 positive regulation of inflammatory response
GO:0060139 positive regulation of apoptotic process by virus
GO:0060326 cell chemotaxis
GO:0070723 response to cholesterol
GO:0070997 neuron death
GO:0071791 chemokine (C-C motif) ligand 5 binding
GO:2000110 negative regulation of macrophage apoptotic process
GO:2000178 negative regulation of neural precursor cell proliferation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000355 Chemokine receptor familyFamilyFamily
IPR002240 CC chemokine receptor 5FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

3 interactions