Entity Details

Primary name CCR2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP51683
EntryNameCCR2_MOUSE
FullNameC-C chemokine receptor type 2
TaxID10090
Evidenceevidence at protein level
Length373
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCcr2

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001974 blood vessel remodeling
GO:0002246 wound healing involved in inflammatory response
GO:0002548 monocyte chemotaxis
GO:0002724 regulation of T cell cytokine production
GO:0002827 positive regulation of T-helper 1 type immune response
GO:0002829 negative regulation of type 2 immune response
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006874 cellular calcium ion homeostasis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0006959 humoral immune response
GO:0006968 cellular defense response
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0009897 external side of plasma membrane
GO:0010574 regulation of vascular endothelial growth factor production
GO:0010820 positive regulation of T cell chemotaxis
GO:0016493 C-C chemokine receptor activity
GO:0016525 negative regulation of angiogenesis
GO:0019233 sensory perception of pain
GO:0019722 calcium-mediated signaling
GO:0019725 cellular homeostasis
GO:0019955 cytokine binding
GO:0019957 C-C chemokine binding
GO:0030097 hemopoiesis
GO:0030334 regulation of cell migration
GO:0030425 dendrite
GO:0032729 positive regulation of interferon-gamma production
GO:0032743 positive regulation of interleukin-2 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035696 monocyte extravasation
GO:0035705 T-helper 17 cell chemotaxis
GO:0035715 chemokine (C-C motif) ligand 2 binding
GO:0035716 chemokine (C-C motif) ligand 12 binding
GO:0035717 chemokine (C-C motif) ligand 7 binding
GO:0043025 neuronal cell body
GO:0043204 perikaryon
GO:0043277 apoptotic cell clearance
GO:0043310 negative regulation of eosinophil degranulation
GO:0045580 regulation of T cell differentiation
GO:0045627 positive regulation of T-helper 1 cell differentiation
GO:0046641 positive regulation of alpha-beta T cell proliferation
GO:0048471 perinuclear region of cytoplasm
GO:0048873 homeostasis of number of cells within a tissue
GO:0050727 regulation of inflammatory response
GO:0050729 positive regulation of inflammatory response
GO:0050870 positive regulation of T cell activation
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0060326 cell chemotaxis
GO:0061756 leukocyte adhesion to vascular endothelial cell
GO:0070098 chemokine-mediated signaling pathway
GO:0071791 chemokine (C-C motif) ligand 5 binding
GO:0090026 positive regulation of monocyte chemotaxis
GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages
GO:0090594 inflammatory response to wounding
GO:0097350 neutrophil clearance
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1903238 positive regulation of leukocyte tethering or rolling
GO:1905517 macrophage migration
GO:2000412 positive regulation of thymocyte migration
GO:2000439 positive regulation of monocyte extravasation
GO:2000451 positive regulation of CD8-positive, alpha-beta T cell extravasation
GO:2000464 positive regulation of astrocyte chemotaxis
GO:2000473 positive regulation of hematopoietic stem cell migration

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000355 Chemokine receptor familyFamilyFamily
IPR002237 CC chemokine receptor 2FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

3 interactions