Entity Details

Primary name FZR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UM11
EntryNameFZR1_HUMAN
FullNameFizzy-related protein homolog
TaxID9606
Evidenceevidence at protein level
Length496
SequenceStatuscomplete
DateCreated2003-10-03
DateModified2021-06-02

Ontological Relatives

GenesFZR1

GO terms

Show/Hide Table
GOName
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007049 cell cycle
GO:0008284 positive regulation of cell population proliferation
GO:0010997 anaphase-promoting complex binding
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031965 nuclear membrane
GO:0040020 regulation of meiotic nuclear division
GO:0045732 positive regulation of protein catabolic process
GO:0051301 cell division
GO:0070306 lens fiber cell differentiation
GO:0070979 protein K11-linked ubiquitination
GO:0090344 negative regulation of cell aging
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1904668 positive regulation of ubiquitin protein ligase activity
GO:1905786 positive regulation of anaphase-promoting complex-dependent catabolic process
GO:1990757 ubiquitin ligase activator activity

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR024977 Anaphase-promoting complex subunit 4, WD40 domainDomainDomain
IPR033010 The WD repeat Cdc20/Fizzy familyFamilyFamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink