Entity Details

Primary name NEK1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP51954
EntryNameNEK1_MOUSE
FullNameSerine/threonine-protein kinase Nek1
TaxID10090
Evidenceevidence at protein level
Length1203
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesNek1

GO terms

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GOName
GO:0000242 pericentriolar material
GO:0001822 kidney development
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0006974 cellular response to DNA damage stimulus
GO:0007049 cell cycle
GO:0007283 spermatogenesis
GO:0010212 response to ionizing radiation
GO:0016301 kinase activity
GO:0034451 centriolar satellite
GO:0035264 multicellular organism growth
GO:0042769 DNA damage response, detection of DNA damage
GO:0046872 metal ion binding
GO:0051301 cell division
GO:0060271 cilium assembly
GO:0071889 14-3-3 protein binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000001 regulation of DNA damage checkpoint

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
NEK1_MOUSEWWTR1_MOUSEBioGRID21474562 details
NEK1_MOUSERIPK1_MOUSEBioGRID29891719 details