Entity Details

Primary name POLH_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y253
EntryNamePOLH_HUMAN
FullNameDNA polymerase eta
TaxID9606
Evidenceevidence at protein level
Length713
SequenceStatuscomplete
DateCreated2005-02-15
DateModified2021-06-02

Ontological Relatives

GenesPOLH

GO terms

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GOName
GO:0000731 DNA synthesis involved in DNA repair
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005657 replication fork
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006282 regulation of DNA repair
GO:0006290 pyrimidine dimer repair
GO:0009314 response to radiation
GO:0010225 response to UV-C
GO:0019985 translesion synthesis
GO:0035861 site of double-strand break
GO:0042276 error-prone translesion synthesis
GO:0046872 metal ion binding
GO:0070987 error-free translesion synthesis
GO:0071494 cellular response to UV-C

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001126 UmuC domainDomainDomain
IPR017961 DNA polymerase, Y-family, little finger domainDomainDomain
IPR036775 DNA polymerase, Y-family, little finger domain superfamilyFamilyHomologous superfamily
IPR041298 DNA polymerase eta, ubiquitin-binding zinc fingerDomainDomain
IPR043128 Reverse transcriptase/Diguanylate cyclase domainFamilyHomologous superfamily
IPR043502 DNA/RNA polymerase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
POLH_HUMANREV1_MOUSEBioGRID30963698 details
POLH_HUMANSHPRH_MOUSEBioGRID21396873 details