Entity Details

Primary name FBW1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y297
EntryNameFBW1A_HUMAN
FullNameF-box/WD repeat-containing protein 1A
TaxID9606
Evidenceevidence at protein level
Length605
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesBTRC

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000209 protein polyubiquitination
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006470 protein dephosphorylation
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007165 signal transduction
GO:0008013 beta-catenin binding
GO:0016032 viral process
GO:0016055 Wnt signaling pathway
GO:0016567 protein ubiquitination
GO:0016874 ligase activity
GO:0019005 SCF ubiquitin ligase complex
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031648 protein destabilization
GO:0033598 mammary gland epithelial cell proliferation
GO:0038061 NIK/NF-kappaB signaling
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042752 regulation of circadian rhythm
GO:0042753 positive regulation of circadian rhythm
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043687 post-translational protein modification
GO:0045309 protein phosphorylated amino acid binding
GO:0045862 positive regulation of proteolysis
GO:0045879 negative regulation of smoothened signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046983 protein dimerization activity
GO:0048511 rhythmic process
GO:0050852 T cell receptor signaling pathway
GO:0051403 stress-activated MAPK cascade
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0060828 regulation of canonical Wnt signaling pathway
GO:0061136 regulation of proteasomal protein catabolic process
GO:0061630 ubiquitin protein ligase activity
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070936 protein K48-linked ubiquitination
GO:0071407 cellular response to organic cyclic compound
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1904668 positive regulation of ubiquitin protein ligase activity
GO:1990756 ubiquitin ligase-substrate adaptor activity
GO:1990757 ubiquitin ligase activator activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR001810 F-box domainDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR020472 G-protein beta WD-40 repeatRepeatRepeat
IPR021977 D domain of beta-TrCPDomainDomain
IPR036047 F-box-like domain superfamilyFamilyHomologous superfamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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