Entity Details

Primary name KDM2A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y2K7
EntryNameKDM2A_HUMAN
FullNameLysine-specific demethylase 2A
TaxID9606
Evidenceevidence at protein level
Length1162
SequenceStatuscomplete
DateCreated2003-11-07
DateModified2021-06-02

Ontological Relatives

GenesKDM2A

GO terms

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GOName
GO:0003712 transcription coregulator activity
GO:0005654 nucleoplasm
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006482 protein demethylation
GO:0008270 zinc ion binding
GO:0010944 negative regulation of transcription by competitive promoter binding
GO:0032452 histone demethylase activity
GO:0032922 circadian regulation of gene expression
GO:0042752 regulation of circadian rhythm
GO:0045322 unmethylated CpG binding
GO:0051864 histone demethylase activity (H3-K36 specific)
GO:0070544 histone H3-K36 demethylation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001810 F-box domainDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR002857 Zinc finger, CXXC-typeDomainDomain
IPR003347 JmjC domainDomainDomain
IPR006553 Leucine-rich repeat, cysteine-containing subtypeRepeatRepeat
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR041070 Jumonji, helical domainDomainDomain

Diseases

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Interactions

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