Entity Details

Primary name RRP44_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y2L1
EntryNameRRP44_HUMAN
FullNameExosome complex exonuclease RRP44
TaxID9606
Evidenceevidence at protein level
Length958
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesDIS3

GO terms

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GOName
GO:0000175 3'-5'-exoribonuclease activity
GO:0000176 nuclear exosome (RNase complex)
GO:0000177 cytoplasmic exosome (RNase complex)
GO:0000178 exosome (RNase complex)
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006364 rRNA processing
GO:0016020 membrane
GO:0016075 rRNA catabolic process
GO:0043488 regulation of mRNA stability
GO:0043928 exonucleolytic catabolism of deadenylated mRNA
GO:0071034 CUT catabolic process

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001900 Ribonuclease II/RDomainDomain
IPR002716 PIN domainDomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR022966 Ribonuclease II/R, conserved siteSiteConserved site
IPR029060 PIN-like domain superfamilyFamilyHomologous superfamily
IPR033770 Exosome complex exonuclease RRP44, S1 domainDomainDomain
IPR033771 Rrp44-like cold shock domainDomainDomain
IPR041505 Dis3-like cold-shock domain 2DomainDomain

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink