Entity Details

Primary name AAKB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y478
EntryNameAAKB1_HUMAN
FullName5'-AMP-activated protein kinase subunit beta-1
TaxID9606
Evidenceevidence at protein level
Length270
SequenceStatuscomplete
DateCreated2001-06-01
DateModified2021-06-02

Ontological Relatives

GenesPRKAB1

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0006633 fatty acid biosynthetic process
GO:0007165 signal transduction
GO:0010628 positive regulation of gene expression
GO:0016236 macroautophagy
GO:0016241 regulation of macroautophagy
GO:0019901 protein kinase binding
GO:0031588 nucleotide-activated protein kinase complex
GO:0035878 nail development
GO:0050790 regulation of catalytic activity
GO:0080090 regulation of primary metabolic process
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1901796 regulation of signal transduction by p53 class mediator

Subcellular Location

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Domains

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DomainNameCategoryType
IPR006828 Association with the SNF1 complex (ASC) domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR032640 AMP-activated protein kinase, glycogen-binding domainDomainDomain
IPR037256 ASC domain superfamilyFamilyHomologous superfamily
IPR039160 5'-AMP-activated protein kinase subunit betaFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00131 Adenosine phosphateDrugbanksmall molecule
DB00273 TopiramateDrugbanksmall molecule
DB00331 MetforminDrugbanksmall molecule
DB00945 Acetylsalicylic acidDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule