Entity Details

Primary name PTPRS_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionB0V2N1
EntryNamePTPRS_MOUSE
FullNameReceptor-type tyrosine-protein phosphatase S
TaxID10090
Evidenceevidence at protein level
Length1907
SequenceStatuscomplete
DateCreated2008-12-16
DateModified2021-06-02

Ontological Relatives

GenesPtprs

GO terms

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GOName
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006470 protein dephosphorylation
GO:0008201 heparin binding
GO:0010977 negative regulation of neuron projection development
GO:0021510 spinal cord development
GO:0021549 cerebellum development
GO:0021766 hippocampus development
GO:0021987 cerebral cortex development
GO:0022038 corpus callosum development
GO:0030285 integral component of synaptic vesicle membrane
GO:0030424 axon
GO:0030426 growth cone
GO:0030517 negative regulation of axon extension
GO:0032687 negative regulation of interferon-alpha production
GO:0032688 negative regulation of interferon-beta production
GO:0034164 negative regulation of toll-like receptor 9 signaling pathway
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0035374 chondroitin sulfate binding
GO:0043204 perikaryon
GO:0043395 heparan sulfate proteoglycan binding
GO:0048671 negative regulation of collateral sprouting
GO:0048681 negative regulation of axon regeneration
GO:0050804 modulation of chemical synaptic transmission
GO:0050808 synapse organization
GO:0061000 negative regulation of dendritic spine development
GO:0090557 establishment of endothelial intestinal barrier
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098978 glutamatergic synapse
GO:0099056 integral component of presynaptic membrane
GO:0099061 integral component of postsynaptic density membrane
GO:0099151 regulation of postsynaptic density assembly
GO:0099560 synaptic membrane adhesion
GO:1905606 regulation of presynapse assembly

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasmic vesicle
Perikaryon

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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