Entity Details

Primary name MYO5A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y4I1
EntryNameMYO5A_HUMAN
FullNameUnconventional myosin-Va
TaxID9606
Evidenceevidence at protein level
Length1855
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesMYO5A

GO terms

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GOName
GO:0000146 microfilament motor activity
GO:0001726 ruffle
GO:0003723 RNA binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006892 post-Golgi vesicle-mediated transport
GO:0007015 actin filament organization
GO:0015031 protein transport
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0016192 vesicle-mediated transport
GO:0016459 myosin complex
GO:0030048 actin filament-based movement
GO:0030050 vesicle transport along actin filament
GO:0030426 growth cone
GO:0031267 small GTPase binding
GO:0032402 melanosome transport
GO:0032433 filopodium tip
GO:0032593 insulin-responsive compartment
GO:0032869 cellular response to insulin stimulus
GO:0042470 melanosome
GO:0043005 neuron projection
GO:0051015 actin filament binding
GO:0070062 extracellular exosome
GO:0072659 protein localization to plasma membrane

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000048 IQ motif, EF-hand binding siteSiteBinding site
IPR001609 Myosin head, motor domainDomainDomain
IPR002710 Dilute domainDomainDomain
IPR004009 Myosin, N-terminal, SH3-likeDomainDomain
IPR008989 Myosin S1 fragment, N-terminalFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036103 Class V myosin, motor domainDomainDomain
IPR036961 Kinesin motor domain superfamilyFamilyHomologous superfamily
IPR037988 Myosin 5a, cargo-binding domainDomainDomain

Diseases

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Interactions

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